Acute myocardial infarction remains a major problem in the western world. Primary angioplasty is often considered a superior first-line option in the treatment of myocardial infarction. Compared to thrombolytic therapy, primary angioplasty offers a lower incidence of mortality and of stroke. The interventional cardiologist is able to diagnose the acute MI immediately and accurately, to assess the restored blood flow, and help the operator obtain better reperfusion in a greater number of patients. Primary Angioplasty explains such procedures. The authors share insights from years of experience in performing PTCA and stenting upon patients immediately upon admission to their center.