Given the continuing development of new statins and their increasing beneficial use in clinical practice as well as the importance of clinical research into the atherosclerotic plaque and its role in cardiovascular and endovascular diseases, Gaw and Shepherd have chosen topics on lipids and atherosclerosis that are of current interest for researchers and clinicians alike. This edition of the Lipids and Atherosclerosis Annual includes chapters on topics of current interest, including the long-term safety of lipid-lowering drugs, the implications of statin therapy on CHD prevention, and drug combination strategies for vascular disease prevention.