Building upon the strengths of the best-selling first edition, Histamine and H1-Antihistamines in Allergic Disease, Second Edition presents the latest advances and current research in histamine, histamine receptors, and H1-antihistamines for practical application in allergy, immunology, dermatology, otolaryngology, and pulmonology. Contains over 2000 contemporary references-300 more than the first edition! This Second Edition offers new chapters detailing · cost-effective techniques to treat and manage allergic rhinoconjunctivitis, urticaria, angioedema, atopic dermatitis, asthma, and anaphylaxis · the use of nonsedating antihistamines in care of the elderly · the safety of specific antihistamines during pregnancy and lactation · quality-of-life comparisons among different H1-antihistamines used in the treatment of allergic rhinitis and provides completely revised and expanded material describing · the role of histamine in the pathogenesis of asthma · regimens for the prevention of anaphylaxis and anaphylactoid reactions · the potential of combined antihistamine and antileukotriene therapy With contributions from more than 20 esteemed international authorities, the Second Edition of Histamine and H1-Antihistamines in Allergic Disease is an in-depth guide suitable for allergists, immunologists, pulmonologists, respiratory specialists, dermatologists, otolaryngologists, pharmacologists, and graduate students in these disciplines.