Written by the foremost author in the field, this book explores the principles of informal logic as applied to clinical problems and the uses of evidence in logical reasoning. It covers general concepts, theories, paradigms, and definitions; EBM reasoning at each step of a clinician's work; and decision making based on the integration of all of the above. The book describes the assessment of diagnosis, treatment, and prognosis in practical clinical medicine; clinical and community health; and methods in various quantitative and qualitative analyses, especially meta-analysis. The innovative blend of informal logic and structured evidence-based reasoning make this book stand out in a crowd.