eBooks - Science & Technology - Biology & Nature - Robert A. Copeland - Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists
Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists eBook
by Robert A. Copeland
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Windows Vista / XP / 2000, Mac OS X, Sony Reader Features
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Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists Summary
| The goal of this book is to provide chemists and pharmacologists with the key information they need to answer questions such as: What opportunities for inhibitor interactions with enzyme targets arise from consideration of the catalytic reaction mechanism? How are inhibitors properly evaluated for potency, selectivity, and mode of action? What are the potential advantages and liabilities of specific inhibition modalities with respect to efficacy in vivo? And finally, what information should medicinal chemists and pharmacologist expect from their biochemistry/enzymology colleagues in order to most effectively pursue lead optimization? |
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eBooks - Titles - Authors - Science & Technology - Biology & Nature - Robert A. Copeland - Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists